SAN FRANCISCO Cheap Nike Air Max 270 Flyknit Army Green Black , May 22 (Xinhua) -- A biochemical self-destruct trigger, a protein called RIPK3, found in many other types of cells appears to guard the lives of brain cells during infection with West Nile virus.
RIPK3 is better known for activating a certain type of cell death during infection or other damaging events in other parts of the body. The death of infected cells in this manner is a protective mechanism that helps the body eliminate the infection.
In a recent Cell paper on how brain cells ward off West Nile virus, University of Washington (UW) researchers who led the research say the chemical pathway doesn't have to sacrifice brain cells to destroy the viruses and recruit the body's defenses against infection, and can preserve the brain's nerve cells, or neurons, by using an alternative approach to summon protection.
During a West Nile virus infection Cheap Women's Nike Air Max 270 Coral Stardust , the activation of RIPK3 in brain cells doesn't cause them to die. That is because its signaling within the central nervous system is not the same as in cell types elsewhere in the body. Its brain-specific role implies that there are central nervous system functions for RIPK3 not observed in other tissues.
"There is something special about neurons, perhaps because they are non-renewable and too important to undergo cell death," said Andrew Oberst, assistant professor of immunology at the University of Washington School of Medicine and senior author on the paper.
RIPK3 responds to the presence of West Nile virus in the brain by placing an order for chemokines, the researchers observed.
The lead author of the paper, Brian Daniels, a UW Medicine postdoctoral fellow in immunology Cheap Nike Air Max 270 Men's Grape , explained that these chemicals underlie a successful ousting of West Nile virus. Chemokines attract an influx of infection-fighting white blood cells.
These efforts contribute to the clearance of the virus from the brain, but not by directly stopping replacement virus from reproducing within brain cells. Instead, the brain tissue undergoes a kind of inflammation that restricts the West Nile virus infection. "RIPK3 acts as part of the milieu of signals that support anti-viral inflammation in the brain," said Daniels.
In a different cell type, such as a fibroblast, the entry of a West Nile virus would result in the cell initiating its own demise.
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BEIJING Cheap Nike Air Max 270 Men's Camo Heel , May 23 (Xinhua) -- A much-anticipated bill to regulate the parking of Beijing's millions of cars will be submitted to the municipal legislature this year, its drafters said.
The rule will promote the use of automated parking meters to discourage unlicensed parking assistants who have become a source of complaints from car-owners. It will also encourage residential communities, businesses and government compounds to open their parking spaces to the public.
More than 1,300 suggestions have been received since members of the public were invited to give their opinions in April, said Jiang Yingming, a city government official in charge of the legislation.
Like many Chinese cities, Beijing has experienced an explosive growth in the number of private cars thanks to rising living standards and dropping car prices. But parking has become a headache for most car-owners as city planners did not foresee the boom of automobiles.
HO CHI MINH CITY Cheap Men's Black God Nike Air Max 270 Flyknit , Aug. 2 (Xinhua) -- Top Vietnamese tennis player Ly Hoang Nam, world No. 1,312, will participate in the men's F26-28 Futures in Egypt, slated for August 10, local newspaper Vietnam News reported Sunday.
The 18-year-old player has so far attended three Futures tournaments in Thailand, Indonesia and Belgium. He entered the quarter-finals in Thailand and Indonesia.
Nam, born in southern Tay Ninh province, became the first Vietnamese to claim a Grand Slam junior title after winning the boys' doubles trophy at the Wimbledon championships, with an Indian partner on July 12.
ARUSHA, Tanzania, June 25 (Xinhua) -- Latifa Felix still recallsthe terrible condition of Tanzania's Ruvu South Forest Reserve tenyears ago when it was overrun by illegal loggers, charcoal makersand invading farmers.
Many invaders of the Tanzania's most important coastal forestwere local villagers Cheap Nike Air Max 270 Men's Light Bone , and Felix, a villager-turned environmentalactivist, faced a tough task changing their minds.
"When we started the intervention ... it wasn't easy task tochange people's mindsets, as Ruvu South Forest Reserve waseverything to many of them," said Felix, now chairperson of theSoga village environment committee
"Forest conservation was depriving their main source of income,as some were engaging in illegal logging Cheap Nike Air Max 270 Men's Midnight Navy , timber and charcoalbusiness," she said.
Fortunately, since 2005 when non-government organizations (NGOs)such as Tanzania Forest Conservation Group (TFCG), CARE-Tanzania,and Tanzania Natural Resource Forum (TNRF) started encouragingvillagers to take part in saving the forest from disappearance,positive changes have ensued.